KMID : 0545120040140051089
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Journal of Microbiology and Biotechnology 2004 Volume.14 No. 5 p.1089 ~ p.1092
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Stimulation of Actinorhodin Production by Streptomyces lividans with a Chromosomally-Integrated Antibiotic Regulatory Gene afsR2
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Kim CY
Park HJ/Yoon YJ/Kang HY/Kim ES
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Abstract
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An actinorhodin nonproducing Streptomyces lividans was converted to an actinorhodin overproducer through a single chromosomal integration of an antibiotic regulatory gene afsR2. This strain exhibited early actinorhodin production and an average of 37.5% higher productivity than the S. lividans containing multiple copies of afsR2 plasmid in a glucosecontaining liquid culture.
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